PGC-1 enhances the expression of nuclear respiratory factor NRF-1, which binds the promoter region of mitochondrial transcription factor A (mtTFA)
ZhangXZhouSLiangYXieGZhuMWangZet al
Because the prescription follows the data, dose titration is built into the model
We suggest glutathione is one such endogenous source, as further impairing glutamate liberation from the cycle diminishes synaptic activity induced by MeAIB, while increasing glutamate availability can rescues the impairment by MeAIB
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60 In hepatoma cells, miR-125b-5p directly targets the downstream gene STAT3 to enhance -catenin phosphorylation